The benefits and harms of Cardiomagnyl

Cardiomagnet belongs to the group of NSAIDs (non-steroidal anti-inflammatory drugs). It is an antiplatelet agent used to prevent acute heart failure and thrombosis. The benefits and harms of Cardiomagnyl are due to its main action. Cardiomagnet is indicated for patients at risk, or with disorders in the functioning of the cardiovascular system.

What is Cardiomagnet for?

Cardiomagnyl has an obvious anti-inflammatory effect due to the irreversible inhibition of cyclooxygenase-1 by blocking and acetylation of thromboxane A2 production. Thus, the aggregation of platelet cell elements in the blood is inhibited. This leads to the prevention of blood clots.

The use of Cardiomagnyl lies in the prevention of the most severe complications associated with the cardiovascular system. The medicine has been used for a long time in the practice of cardiology. It can cause harm in exceptional cases, for example, when the recommended dosage is exceeded.

Composition and form of release

Cardiomagnet is an oral tablet that is shaped like a heart. The tablet preparation is distinguished by its white color and the presence of a film shell.

The use of Cardiomagnyl in the treatment of pathologies is due to the content of two active substances:

• acetylsalicylic acid (75 mg);
• magnesium hydrochloride (15.2 mg).

Excipients include:

• magnesium stearate;
• potato and corn starch;
• microcrystalline cellulose.

The shell of Cardiomagnyl tablets consists of talc, hypromellose, propylene glycol. The drug is available in brown opaque glass bottles. Cardiomagnet (100 tablets) is available in a dosage of 75 and 150 mg.

The benefits of Cardiomagnyl: indications for use

The use of tablets is a pronounced antiplatelet effect. Significant doses of acetylsalicylic acid produce anti-inflammatory effects. The benefit lies in eliminating inflammation, which is accompanied by pain and fever. If Cardiomagnet is used in small doses, platelets sticking together and the formation of blood clots can be prevented.

The anti-inflammatory effect is due to inhibition of:

• Cyclooxygenase-1. It is directly involved in the production of prostaglandins, which are responsible for the occurrence of the inflammatory reaction.
• Thromboxane A synthesis. It is observed in platelets and is responsible for adhesion or aggregation.

Magnesium hydroxide, which is part of the drug Cardiomagnyl, benefits in the form of protecting the mucous membrane of the digestive tract from the harm caused by acetylsalicylic acid.The interaction of the substance, hydrochloric acid and gastric juice is noted. The walls of the organ are covered with a protective film.

Cardiomagnet is beneficial for pathological conditions in the cardiovascular system and the risk of their occurrence. The tablets can be used for a long time to prevent dangerous conditions. The benefits of treatment with Cardiomagnil can be expected with the following indications for admission:

• unstable angina;
• prevention of heart failure and thrombosis in the presence of diabetes mellitus, hypertension, overweight, old age and smoking;
• prevention of recurrence of thrombosis and heart attack;
• prevention of thromboembolism after coronary artery bypass grafting or coronary angioplasty on the vessels;
• coronary heart disease;
• decreased blood supply to the brain;
• migraine.

The effect is achieved by long-term administration of the drug. To prevent Cardiomagnet from causing harm to health, it should be taken exclusively under the supervision of a physician.

How to take Cardiomagnet

The tablets are recommended to be washed down with clean water and swallowed whole. Sometimes it can be difficult to swallow. In such cases, it is allowed to take the drug in powder form. It is allowed to break the tablet along the risks.

Dosage

The dosage of Cardiomagnyl is determined by the doctor after the examination. Chronic pathologies in the anamnesis, the presence of regularly taken medications are essential. The prescribed dosage depends on the main indications for admission, which are presented in the table.

Recommendations for use

The medicine is used for prophylactic and therapeutic purposes for pathologies of the heart and blood vessels. The benefit of using tablets in small dosages is to reduce the risk of disease by 25%, which is especially important for elderly patients. Cardiomagnet is beneficial for atherosclerosis, diabetes mellitus, hypertension, obesity, high cholesterol levels, and a family history.

Acetylsalicylic acid is considered as a factor in the onset of bronchospasm. The substance can be harmful to people with a history of allergies and asthma. Blood clotting worsens during admission, which causes bleeding during surgery.

The benefits of Cardiomagnyl are expressed in the absence of an effect on concentration. The medicine can be taken by people working in enterprises and transport managers.

The benefits and harms of Cardiomagnet tablets depend on the gender of the patients. According to the results of the conducted studies, taking the medicine in men prevents a heart attack, but not a stroke. In women under 65, it is the risk of stroke that decreases, but not for heart attack. After a woman reaches the specified age, the use of Cardiomagnyl also lies in the prevention of heart attack.

Is Cardiomagnet possible during pregnancy and lactation

One of the contraindications to taking the drug regularly is pregnancy in the first and third trimester. This is due to the harm that acetylsalicylic acid can do.

The use of Cardiomagnyl in the first trimester can cause irreversible disturbances in fetal development. Significant doses of the drug provoke bleeding during childbirth. The risk of intracranial hemorrhage in a child is not excluded.

Taking the drug in the second trimester is possible. However, the physician must assess the benefits and possible harm.

The active ingredients of Cardiomagnyl penetrate into breast milk. Regular medication during lactation is prohibited.

Side effects

In addition to benefits, Cardiomagnet can harm the body, which is expressed in the occurrence of undesirable reactions from the functioning of organs and systems:

1. Allergy. One of the common manifestations is urticaria. Quincke's edema and anaphylactic shock are rare.
2. Gastrointestinal organs. While taking it, symptoms such as heartburn, nausea or vomiting may occur. Stomach pains sometimes indicate stomach ulcers. In rare cases, bleeding, ulcer perforation, esophagitis, irritable bowel syndrome, colitis occur.
3. Respiratory system. There is a frequent development of bronchospasm.
4. Hematopoiesis. The appearance of anemia, thrombocytopenia, neutropenia is possible.
5. Central nervous system. There are signs of sleep disturbance, dizziness, tinnitus.

The risk of side reactions increases with an increase in the dose of the main active ingredient - acetylsalicylic acid. Benefit while taking the drug is achieved exclusively through the competent selection of the required dosage, which corresponds to the individual characteristics of the patient and his diagnosis.

Harm of Cardiomagnet: consequences of an overdose

Despite the fact that Cardiomagnet is beneficial for diseases of the heart and blood vessels, if the dosage is exceeded, it can cause serious harm to health. Experts classify the severity of an overdose as:

1. Average. There is nausea and vomiting, tinnitus, impaired coordination. Hearing worsens, confusion and dizziness occur. Patients are prescribed gastric lavage and an adequate dose of activated carbon. Treatment depends on the clinical picture associated with an overdose.
2. Heavy. Fever, coma, respiratory and cardiovascular insufficiency, severe hypoglycemia are noted. Treatment is carried out in a hospital setting. Patients are shown intensive therapy, which includes the introduction of special alkaline solutions, the formation of diuresis and gastric lavage, hemodialysis.

Compatibility of Cardiomagnyl with other drugs

Cardiomagnet can enhance the effect of some drugs if used together. Experts call the following drugs that are affected by taking Cardiomagnyl:

1. Methotrexate. Decreased renal clearance, destruction of bonds with proteins.
2. Heparin and indirect anticoagulants. Platelets change how they function. Anticoagulants are displaced from their bonds with proteins.
3. Antiplatelet and hypoglycemic agents - ticlopidine.
4. Preparations containing ethanol.
5. Insulin and hypoglycemic drugs.
6. Digoxin. There is a decrease in renal excretion.
7. Valproic acid. Forcing it out of bonds with proteins.

Cardiomagnet suppresses the action of:

• uricosuric agents;
• antacids and cholestyramine.

Contraindications

The instruction of the drug indicates several main contraindications, in the presence of which Cardiomagnet can cause harm:

• cerebral hemorrhage;
• lack of vitamin K, thrombocytopenia, hemorrhagic diathesis, which are harmful in the form of bleeding;
• exacerbation of stomach ulcers and bleeding;
• the occurrence of bronchial asthma during treatment with NSAIDs;
• severe renal dysfunction;
• pregnancy in the 1st and 3rd trimesters;
• lactation;
• hypersensitivity to the components of Cardiomagnyl;
• age up to 18 years;
• renal failure
• therapy with methotrexate.

Cardiomagnet should be taken with extreme caution because of the potential harm in the following cases:

• gout;
• renal or hepatic impairment;
• hyperuricemia;
• history of stomach ulcers and bleeding;
• bronchial asthma;
• polyposis in the nose;
• allergy;
• second trimester pregnancy.

In some cases, taking Cardiomagnet tablets can be harmful. That is why, when identifying contraindications, they should not be ignored. In the presence of relative contraindications, the decision in favor of admission should be made by the doctor.

There is also a risk of bleeding before and after surgery, especially when combined with anticoagulants, thrombolytics and antiplatelet agents. During treatment, bronchospasm and other harmful reactions indicating hypersensitivity may appear.

With the simultaneous administration of Methotrexate, the risk of adverse reactions from the hematopoietic system increases many times. The harm of Cardiomagnyl is the development of gout in the presence of a predisposition. Patients with diabetes should be careful.

High doses of Cardiomagnyl tablets provoke hypoglycemic effects. Excess of the dosage recommended by the doctor causes harm to the body, which can lead to bleeding from the gastrointestinal tract. The risk of this complication is higher in older patients.

Analogs: what can replace Cardiomagnet

The medicine has analogues that differ in similar action. Experts call the following drugs that can replace Cardiomagnet:

1. Thrombo-Ass. It belongs to the group of NSAIDs and is an antiplatelet agent. The preparation contains the main active ingredient - acetylsalicylic acid (50, 100 mg).
2. Aspirin cardio. The medicine is produced in Switzerland. One tablet contains acetylsalicylic acid - 300 mg. Aspirin cardio is available in cardboard boxes with a different number of tablets (10, 14 pcs.).
3. Thrombopol. A Polish-made drug containing acetylsalicylic acid (150 mg). The number of tablets in one package is 10 pieces.
4. Aspikor. The drug is produced in Russia. Its benefits are due to the content of acetylsalicylic acid in a dose of 100 mg (10 and 20 tablets per pack).

Analogues of Cardiomagnyl have one active ingredient. This means that the benefits and harms of taking them are identical. However, in the composition of the Japanese medicine, magnesium hydrochloride is also determined, which prevents irritation of the mucous membranes of the stomach. Thus, Cardiomagnyl tablets cause less pronounced harm to health by reducing the risk of side effects.

Which is better: Cardiomagnet or Trombital

Medicines thin the blood and improve its rheological properties. The composition of the drugs is identical, the difference lies in the release of a specific pharmaceutical company and the country of manufacture.

Cardiomagnet is a Japanese drug produced in Russia, Germany and Denmark. Generic Trombital is a Russian medicine. The product is also available in dosages of 75 and 150 mg. Each package contains 30, 100 tablets.

Medicines have similar effects and benefits. Cardiomagnet and Trombital are used as a treatment and prevention of heart and vascular diseases. The harm is represented by the side effects of acetylsalicylic acid. The active ingredient, when taken for a long time, irritates the mucous membranes of the stomach, provoking an ulcer. The benefits of the magnesium included in the formulation implies protection against this. However, medications are not prescribed for exacerbations of gastritis or ulcers.

Thrombital as well as Cardiomagnet have the same indications:

• hypertension;
• high concentration of cholesterol;
• excess weight;
• elderly age.

The benefits of drugs are provided due to the absence of sugars in the composition. This allows them to be used with a history of diabetes mellitus.

Medicines vary significantly in price. Buying a generic drug will cost 30-40% less than the original.

Reviews

The benefits and harms of Cardiomagnyl are evidenced by patient reviews.

The benefits and harms of Cardiomagnyl are due to its main therapeutic effect. The drug therapy can effectively prevent serious vascular and heart diseases. Cardiomagnet is recommended to be used both for treatment and for the prevention of pathologies.